Issue 3, 2018

A self-assessed photosensitizer: inducing and dual-modal phosphorescence imaging of mitochondria oxidative stress

Abstract

Two novel Ir(III)–nitroxide conjugates have been synthesized as mitochondria-targeted multi-functional theranostic photosensitizers, capable of simultaneously inducing and dual-modal phosphorescence imaging of mitochondrial oxidative stress under two-photon excitation, thus realizing the photodynamic therapy of cancer and self-assessment of their PDT efficacies.

Graphical abstract: A self-assessed photosensitizer: inducing and dual-modal phosphorescence imaging of mitochondria oxidative stress

Associated articles

Supplementary files

Article information

Article type
Communication
Submitted
09 Oct 2017
Accepted
05 Dec 2017
First published
05 Dec 2017

Chem. Commun., 2018,54, 271-274

A self-assessed photosensitizer: inducing and dual-modal phosphorescence imaging of mitochondria oxidative stress

Y. Jing, Q. Cao, L. Hao, G. Yang, W. Hu, L. Ji and Z. Mao, Chem. Commun., 2018, 54, 271 DOI: 10.1039/C7CC07797A

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