Issue 1, 2018

Branched peptides for enzymatic supramolecular hydrogelation

Abstract

Here we show the use of branched peptides (i.e., isopeptides) as the substrates of proteases for generating supramolecular hydrogels via enzymatically clipping the branch off the peptides. As the first report of using a protease to cut branched peptides to enable a molecular process for converting nanostructures, this work illustrates a fundamentally new molecular motif for exploring the applications of protease-instructed self-assembly for soft materials.

Graphical abstract: Branched peptides for enzymatic supramolecular hydrogelation

Supplementary files

Article information

Article type
Communication
Submitted
01 Nov 2017
Accepted
21 Nov 2017
First published
06 Dec 2017

Chem. Commun., 2018,54, 86-89

Branched peptides for enzymatic supramolecular hydrogelation

H. He, H. Wang, N. Zhou, D. Yang and B. Xu, Chem. Commun., 2018, 54, 86 DOI: 10.1039/C7CC08421H

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