Issue 21, 2018

Dual polarity MALDI imaging mass spectrometry on the same pixel points reveals spatial lipid localizations at high-spatial resolutions in rat small intestine

Abstract

Sensitive laser desorption/ionization obtained via a sublimation-coated 1,5-diaminonaphthalene (1,5-DAN) matrix allowed dual polarity MALDI-IMS analysis on the same pixel points across the jejunal mucosal region in rat small intestine which yielded high-spatial-resolution (10 μm) ion images of several lipid species correlated with the same histological features.

Graphical abstract: Dual polarity MALDI imaging mass spectrometry on the same pixel points reveals spatial lipid localizations at high-spatial resolutions in rat small intestine

Supplementary files

Article information

Article type
Communication
Submitted
23 Mar 2018
Accepted
02 May 2018
First published
03 May 2018
This article is Open Access
Creative Commons BY-NC license

Anal. Methods, 2018,10, 2428-2435

Dual polarity MALDI imaging mass spectrometry on the same pixel points reveals spatial lipid localizations at high-spatial resolutions in rat small intestine

I. Kaya, E. Jennische, S. Lange and P. Malmberg, Anal. Methods, 2018, 10, 2428 DOI: 10.1039/C8AY00645H

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