Issue 8, 2020
From the journal:

Chemical Communications

A facile analytical method for reliable selectivity examination in cofactor NADH regeneration†

Tony Saba,a   Joseph W. H. Burnett,a   Jianwei Li,a   Panagiotis N. Kechagiopoulos ORCID logo a  and  Xiaodong Wang ORCID logo ‡*a  

* Corresponding authors

a Chemical and Materials Engineering, School of Engineering, University of Aberdeen, Aberdeen AB24 3UE, UK
E-mail: xiaodong.wang@lancaster.ac.uk

Abstract

This study demonstrates a novel method to quantify selective (1,4-NADH) and unselective products (1,2- and 1,6-NADH) in NADH regeneration using combined UV-Vis spectroscopy and biological assays. The validity of the proposed method was tested in the Pt/C promoted NAD+ hydrogenation using hydrogen as reducing agent.

Graphical abstract: A facile analytical method for reliable selectivity examination in cofactor NADH regeneration

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Article information

DOI
https://doi.org/10.1039/C9CC07805C
Article type
Communication
Submitted
04 Oct 2019
Accepted
18 Dec 2019
First published
18 Dec 2019
This article is Open Access
Creative Commons BY license

Chem. Commun., 2020,56, 1231-1234

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A facile analytical method for reliable selectivity examination in cofactor NADH regeneration

T. Saba, J. W. H. Burnett, J. Li, P. N. Kechagiopoulos and X. Wang, Chem. Commun., 2020, 56, 1231 DOI: 10.1039/C9CC07805C

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