Issue 1, 2020, Issue in Progress
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RSC Advances

Palladium mediated domino reaction: synthesis of isochromenes under aqueous medium†

Lavisha Punia,a   Karu Ramesha  and  Gedu Satyanarayana ORCID logo *a  

* Corresponding authors

a Department of Chemistry, Indian Institute of Technology (IIT) Hyderabad, Kandi – 502 285, Sangareddy District, Telangana, India
E-mail: gvsatya@iith.ac.in
Web: https://sites.google.com/site/gsresearchgrouphomepage/home
Fax: +91 40 2301 6032

Abstract

Isochromenes have been synthesized using palladium-catalyzed C–C and C–O bond forming reactions starting from ortho-bromo tertiary benzylic alcohols and internal acetylenes. Notably, this domino process is feasible by using the green solvent, water. The protocol exhibited a broad substrate scope and afforded various isochromenes.

Graphical abstract: Palladium mediated domino reaction: synthesis of isochromenes under aqueous medium

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Article information

DOI
https://doi.org/10.1039/C9RA08792C
Article type
Paper
Submitted
26 Oct 2019
Accepted
15 Dec 2019
First published
02 Jan 2020
This article is Open Access
Creative Commons BY license

RSC Adv., 2020,10, 338-349

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Palladium mediated domino reaction: synthesis of isochromenes under aqueous medium

L. Punia, K. Ramesh and G. Satyanarayana, RSC Adv., 2020, 10, 338 DOI: 10.1039/C9RA08792C

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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