Issue 26, 2020

Unlocking the direct photocatalytic difluoromethylation of C[double bond, length as m-dash]N bonds

Abstract

The current study presents a direct CF2H radical addition to C[double bond, length as m-dash]N bonds predicated on the photocatalytic activation of commercially available zinc difluoromethanesulfinate. The mild conditions in place lead to impressive structural diversity, as quinoxalinones and dibenzazepines, among others, are successfully functionalized.

Graphical abstract: Unlocking the direct photocatalytic difluoromethylation of C [[double bond, length as m-dash]] N bonds

Supplementary files

Article information

Article type
Communication
Submitted
30 Jan 2020
Accepted
27 Feb 2020
First published
27 Feb 2020
This article is Open Access
Creative Commons BY license

Chem. Commun., 2020,56, 3769-3772

Unlocking the direct photocatalytic difluoromethylation of C[double bond, length as m-dash]N bonds

A. F. Garrido-Castro, A. Gini, M. C. Maestro and J. Alemán, Chem. Commun., 2020, 56, 3769 DOI: 10.1039/D0CC01353F

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