Issue 92, 2020

Transition metal-free and regioselective vinylation of phosphine oxides and H-phosphinates with VBX reagents

Abstract

A series of phosphine oxides and H-phosphinates were vinylated in the presence of the iodine(III) reagents vinylbenziodoxolones (VBX), providing the corresponding alk-1-enyl phosphine oxides and alk-1-enyl phosphinates in good yields with complete chemo- and regioselectivity. The vinylation proceeds in open flask under mild and transition metal-free conditions.

Graphical abstract: Transition metal-free and regioselective vinylation of phosphine oxides and H-phosphinates with VBX reagents

Supplementary files

Article information

Article type
Communication
Submitted
05 Sep 2020
Accepted
27 Oct 2020
First published
27 Oct 2020
This article is Open Access
Creative Commons BY license

Chem. Commun., 2020,56, 14389-14392

Transition metal-free and regioselective vinylation of phosphine oxides and H-phosphinates with VBX reagents

L. Castoldi, A. A. Rajkiewicz and B. Olofsson, Chem. Commun., 2020, 56, 14389 DOI: 10.1039/D0CC05992G

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