Issue 49, 2020, Issue in Progress

Water-triggered union of multi-component reactions towards the synthesis of a 4H-chromene hybrid scaffold

Abstract

An unprecedented union of multi-component reactions to construct pyrazole- and pyranopyrazole-adorned 4H-chromene from simple reactants in water at ambient temperature is reported. This innovative tactic has integrated two distinct four-component reactions (4CRs) that occur transiently to form four new heterocycles via ten covalent bonds in a single step.

Graphical abstract: Water-triggered union of multi-component reactions towards the synthesis of a 4H-chromene hybrid scaffold

Supplementary files

Article information

Article type
Paper
Submitted
09 Jun 2020
Accepted
13 Jul 2020
First published
06 Aug 2020
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2020,10, 29109-29113

Water-triggered union of multi-component reactions towards the synthesis of a 4H-chromene hybrid scaffold

K. Kumaravel, B. Rajarathinam and G. Vasuki, RSC Adv., 2020, 10, 29109 DOI: 10.1039/D0RA05105E

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