Stability, toxicity and differential cellular uptake of protein passivated-Fe3O4nanoparticles

Avinash Bajaj; Bappaditya Samanta; Haoheng Yan; D. Joseph Jerry; Vincent M. Rotello

doi:10.1039/B901616C

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Stability, toxicity and differential cellular uptake of protein passivated-Fe₃O₄nanoparticles†‡

Avinash Bajaj,^a Bappaditya Samanta,^a Haoheng Yan,^b D. Joseph Jerry^b and Vincent M. Rotello*^a

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* Corresponding authors

^a Department of Chemistry, University of Massachusetts, USA
E-mail: rotello@chem.umass.edu
Fax: +1-413-545-4490
Tel: +1-413-545-2058

^b Department of Veterinary and Animal Science, University of Massachusetts, USA

Abstract

We have explored the mechanism and differential uptake of BSA coated Fe₃O₄nanoparticles (NPs) by different cancerous and isogenic cell types.

This article is part of the themed collection: Inorganic nanoparticles for biological sensing, imaging and therapeutics

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Supplementary files

Stability assay data of nanoparticles, uptake in differentserum conditions and cell viability assay in different celltypes PDF (239K)

Article information

DOI: https://doi.org/10.1039/B901616C
Article type: Communication
Submitted: 26 Jan 2009
Accepted: 24 Mar 2009
First published: 08 Apr 2009

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J. Mater. Chem., 2009,19, 6328-6331

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Stability, toxicity and differential cellular uptake of protein passivated-Fe₃O₄nanoparticles

A. Bajaj, B. Samanta, H. Yan, D. J. Jerry and V. M. Rotello, J. Mater. Chem., 2009, 19, 6328 DOI: 10.1039/B901616C

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Journal of Materials Chemistry