Issue 16, 2011

Revealing the nature of thio-click reactions on the solid phase

Abstract

Thiol- and yne-functionalized beads were manufactured in a simple microfluidic setup. While CuAAC and thiol–yne reactions were performed on yne-functionalized beads, 9 different thiol–X reactions were compared, in terms of kinetics and conversion, on thiol-functionalized beads.

Graphical abstract: Revealing the nature of thio-click reactions on the solid phase

Supplementary files

Article information

Article type
Communication
Submitted
02 Dec 2010
Accepted
04 Mar 2011
First published
21 Mar 2011

Chem. Commun., 2011,47, 4652-4654

Revealing the nature of thio-click reactions on the solid phase

M. T. Gokmen, J. Brassinne, R. A. Prasath and F. E. Du Prez, Chem. Commun., 2011, 47, 4652 DOI: 10.1039/C0CC05340F

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