Issue 3, 2012

Enhanced reduction of C–N multiple bonds using sodium borohydride and an amorphous nickel catalyst

Abstract

Amorphous nickel powder (Ni0) was utilised as a catalyst under mild, aqueous, basic conditions for enhancing the sodium borohydride-mediated reduction of C–N multiple bonds such as oximes, imines, hydrazones and nitriles to produce the corresponding amines in good to excellent yields.

Graphical abstract: Enhanced reduction of C–N multiple bonds using sodium borohydride and an amorphous nickel catalyst

Supplementary files

Article information

Article type
Paper
Submitted
28 Aug 2011
Accepted
30 Sep 2011
First published
03 Oct 2011

Org. Biomol. Chem., 2012,10, 663-670

Enhanced reduction of C–N multiple bonds using sodium borohydride and an amorphous nickel catalyst

S. Liu, Y. Yang, X. Zhen, J. Li, H. He, J. Feng and A. Whiting, Org. Biomol. Chem., 2012, 10, 663 DOI: 10.1039/C1OB06471A

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