Issue 23, 2011

Thermally sensitive dual fluorescent polymeric micelles for probing cell properties

Abstract

Dual fluorescent micelles with a hydrophobic probe (HMA) embedded in the micelle core and a hydrophilic probe (TRITC) attached on the micelle corona were prepared. These micelles can act as nanometre-sized thermal sensors. Within a short temperature range, the fluorescent emission of the micelles changes strongly and reversibly as a function of temperature. These micelles can be easily taken up by human HeLa cells and can potentially be used as intracellular thermometers.

Graphical abstract: Thermally sensitive dual fluorescent polymeric micelles for probing cell properties

Supplementary files

Article information

Article type
Paper
Submitted
22 Aug 2011
Accepted
09 Sep 2011
First published
14 Oct 2011

Soft Matter, 2011,7, 11211-11215

Thermally sensitive dual fluorescent polymeric micelles for probing cell properties

F. Li, A. H. Westphal, A. T. M. Marcelis, E. J. R. Sudhölter, M. A. Cohen Stuart and F. A. M. Leermakers, Soft Matter, 2011, 7, 11211 DOI: 10.1039/C1SM06597A

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