Issue 4, 2012

Copper-promoted probe for nitric oxide based on o-phenylenediamine: Large blue-shift in absorption and fluorescence enhancement

Abstract

We developed a new o-phenylenediamine-based compound as a turn-on fluorescent probe for nitric oxide (NO) with a large blue shift in absorption. It showed high selectivity and sensitivity toward nitric oxide over other ROS and RNS species in neutral buffer solution. The analytical detection limit (ADL) was 30 nM. As far as we are aware this is the first o-phenylenediamine-based NO probe using Cu2+ as a promoter.

Graphical abstract: Copper-promoted probe for nitric oxide based on o-phenylenediamine: Large blue-shift in absorption and fluorescence enhancement

Supplementary files

Article information

Article type
Paper
Submitted
12 Jan 2012
Accepted
19 Feb 2012
First published
16 Mar 2012

Anal. Methods, 2012,4, 919-922

Copper-promoted probe for nitric oxide based on o-phenylenediamine: Large blue-shift in absorption and fluorescence enhancement

X. Sun, Y. Xu, W. Zhu, C. He, L. Xu, Y. Yang and X. Qian, Anal. Methods, 2012, 4, 919 DOI: 10.1039/C2AY25039J

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