Issue 75, 2012

Pd-catalyzed double C–H bond activation of diaryl ketones for the synthesis of fluorenones

Abstract

An efficient synthesis of fluorenones from diaryl ketones by Pd-catalyzed oxidative cyclization is described. A possible mechanism involving a carbonyl group assisted ortho-C–H activation and cyclometalation followed by a second C–H activation to form a six-membered palladacycle and reductive elimination is proposed.

Graphical abstract: Pd-catalyzed double C–H bond activation of diaryl ketones for the synthesis of fluorenones

Supplementary files

Article information

Article type
Communication
Submitted
18 Jun 2012
Accepted
02 Aug 2012
First published
02 Aug 2012

Chem. Commun., 2012,48, 9379-9381

Pd-catalyzed double C–H bond activation of diaryl ketones for the synthesis of fluorenones

P. Gandeepan, C. Hung and C. Cheng, Chem. Commun., 2012, 48, 9379 DOI: 10.1039/C2CC34344D

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