Issue 8, 2012
From the journal:

Lab on a Chip

Microfluidics meets soft layer-by-layer films: selective cell growth in 3D polymer architectures†

Narayanan Madaboosi,ab   Katja Uhlig,a   Stephan Schmidt,a   Magnus S. Jäger,a   Helmuth Möhwald,b   Claus Duschla  and  Dmitry V. Volodkin*a  

* Corresponding authors

a Fraunhofer Institute for Biomedical Engineering, Am Mühlenberg 13, 14476 Potsdam-Golm, Germany
E-mail: Dmitry.Volodkin@ibmt.fraunhofer.de

b Max Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, 14476 Potsdam-Golm, Germany

Abstract

We present here the micropatterns of layer-by-layer (LbL) assembled soft films generated using microfluidic platform that can be exploited for selective cell growth. Using this method, the issue of cell adhesion and spreading on soft LbL-derived films, and simultaneous utilisation of such unmodified soft films to exploit their reservoir properties are addressed. This also paves the way for extending the culture of cells to soft films and other demanding applications like triggered release of biomolecules.

Graphical abstract: Microfluidics meets soft layer-by-layer films: selective cell growth in 3D polymer architectures

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Article information

DOI
https://doi.org/10.1039/C2LC40058H
Article type
Communication
Submitted
13 Jan 2012
Accepted
13 Feb 2012
First published
15 Feb 2012

Lab Chip, 2012,12, 1434-1436

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Microfluidics meets soft layer-by-layer films: selective cell growth in 3D polymer architectures

N. Madaboosi, K. Uhlig, S. Schmidt, M. S. Jäger, H. Möhwald, C. Duschl and D. V. Volodkin, Lab Chip, 2012, 12, 1434 DOI: 10.1039/C2LC40058H

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