Issue 5, 2012

Cytisine: a natural product lead for the development of drugs acting at nicotinic acetylcholine receptors

Abstract

Covering: up to the end of 2011

This review covers classical and modern structural modifications of the alkaloid, the more recent (since 2007) syntheses of cytisine and analogues, and the pharmacology of these compounds, with emphasis on their interactions with nicotinic receptors. 89 references are cited.

Graphical abstract: Cytisine: a natural product lead for the development of drugs acting at nicotinic acetylcholine receptors

Article information

Article type
Review Article
Submitted
01 Dec 2011
First published
27 Feb 2012

Nat. Prod. Rep., 2012,29, 555-567

Cytisine: a natural product lead for the development of drugs acting at nicotinic acetylcholine receptors

E. G. Pérez, C. Méndez-Gálvez and B. K. Cassels, Nat. Prod. Rep., 2012, 29, 555 DOI: 10.1039/C2NP00100D

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