Issue 17, 2012

Copper-mediated domino synthesis of pyrimido[4,5-b]carbazolones via Ullmann N-arylation and aerobic oxidative C–H amidation

Abstract

New pyrimido[4,5-b]carbazolone derivatives have been synthesized through cascade Ullmann N-arylation and aerobic oxidative C–H amidation reactions catalyzed by CuBr under air and ligand-free conditions.

Graphical abstract: Copper-mediated domino synthesis of pyrimido[4,5-b]carbazolones via Ullmann N-arylation and aerobic oxidative C–H amidation

Supplementary files

Article information

Article type
Paper
Submitted
26 Dec 2011
Accepted
20 Feb 2012
First published
21 Feb 2012

Org. Biomol. Chem., 2012,10, 3417-3423

Copper-mediated domino synthesis of pyrimido[4,5-b]carbazolones via Ullmann N-arylation and aerobic oxidative C–H amidation

D. K. Sreenivas, N. Ramkumar and R. Nagarajan, Org. Biomol. Chem., 2012, 10, 3417 DOI: 10.1039/C2OB07179G

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