Issue 31, 2012

Copper-catalyzed domino coupling reaction: an efficient method to synthesize oxindoles

Abstract

An efficient and novel procedure for a copper catalyzed domino coupling reaction has been developed, which afforded various oxindoles in good to excellent yields with tolerance of various substituents. In addition, this method could be applied to synthesize horsfiline and coerulescine in few steps with high total yields.

Graphical abstract: Copper-catalyzed domino coupling reaction: an efficient method to synthesize oxindoles

Supplementary files

Article information

Article type
Paper
Submitted
30 Apr 2012
Accepted
11 Jun 2012
First published
13 Jun 2012

Org. Biomol. Chem., 2012,10, 6404-6409

Copper-catalyzed domino coupling reaction: an efficient method to synthesize oxindoles

J. Hsieh, A. Cheng, J. Fu and T. Kang, Org. Biomol. Chem., 2012, 10, 6404 DOI: 10.1039/C2OB26110C

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