Issue 5, 2013
From the journal:

Soft Matter

TEM imaging of unstained DNA nanostructures using suspended graphene†

Susan Buckhout-White,*ab   Jeremy T. Robinson,c   Nabil D. Bassim,d   Ellen R. Goldman,b   Igor L. Medintzb  and  Mario G. Ancona*c  

* Corresponding authors

a George Mason University, 10910 University Blvd, MS 4E3, Manassas, VA 20110, USA
E-mail: susan.buckhout-white.ctr@nrl.navy.mil

b Center for Bio/Molecular Science and Engineering, Code 6900, U.S. Naval Research Laboratory, Washington, DC 20375, USA

c Electronic Science and Technology Division, Code 6876, U.S. Naval Research Laboratory, Washington, DC 20375, USA
E-mail: mario.ancona@nrl.navy.mil

d Materials Science and Technology Division, Code 6366, U.S. Naval Research Laboratory, Washington, DC 20375, USA

Abstract

We demonstrate a method for imaging unstained DNA nanostructures with transmission electron microscopy via suspended graphene supports. Central to the technique is a sacrificial silicon membrane beneath the graphene that provides mechanical support during aqueous sample deposition but is then eliminated in a final step using a XeF2 dry etch.

Graphical abstract: TEM imaging of unstained DNA nanostructures using suspended graphene

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Article information

DOI
https://doi.org/10.1039/C2SM26950C
Article type
Communication
Submitted
22 Aug 2012
Accepted
12 Nov 2012
First published
28 Nov 2012

Soft Matter, 2013,9, 1414-1417

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TEM imaging of unstained DNA nanostructures using suspended graphene

S. Buckhout-White, J. T. Robinson, N. D. Bassim, E. R. Goldman, I. L. Medintz and M. G. Ancona, Soft Matter, 2013, 9, 1414 DOI: 10.1039/C2SM26950C

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