Issue 7, 2013
From the journal:

Journal of Materials Chemistry B

Graphene-incorporated chitosan substrata for adhesion and differentiation of human mesenchymal stem cells†

Jangho Kim,‡a   Yang-Rae Kim,‡b   Yeonju Kim,c   Ki Taek Lim,a   Hoon Seonwoo,a   Subeom Park,b   Sung-Pyo Cho,b   Byung Hee Hong,b   Pill-Hoon Choung,d   Taek Dong Chung,*b   Yun-Hoon Choung*c  and  Jong Hoon Chung*ae  

* Corresponding authors

a Department of Biosystems & Biomaterials Science and Engineering, Seoul National University, Seoul 151-742, Republic of Korea
E-mail: jchung@snu.ac.kr

b Department of Chemistry, Seoul National University, Seoul 151-747, Republic of Korea
E-mail: tdchung@snu.ac.kr

c Department of Otolaryngology, Ajou University School of Medicine, Suwon 443-721, Republic of Korea
E-mail: yhc@ajou.ac.kr

d Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University, Seoul, Republic of Korea

e Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-742, Republic of Korea

Abstract

A simple method that uses graphene to fabricate nanotopographic substrata was reported for stem cell engineering. Graphene-incorporated chitosan substrata promoted adhesion and differentiation of human mesenchymal stem cells (hMSCs). In addition, we proposed that nanotopographic cues of the substrata could enhance cell–cell and cell–material interactions for promoting functions of hMSCs.

Graphical abstract: Graphene-incorporated chitosan substrata for adhesion and differentiation of human mesenchymal stem cells

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Article information

DOI
https://doi.org/10.1039/C2TB00274D
Article type
Communication
Submitted
18 Oct 2012
Accepted
02 Jan 2013
First published
04 Jan 2013

J. Mater. Chem. B, 2013,1, 933-938

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Graphene-incorporated chitosan substrata for adhesion and differentiation of human mesenchymal stem cells

J. Kim, Y. Kim, Y. Kim, K. T. Lim, H. Seonwoo, S. Park, S. Cho, B. H. Hong, P. Choung, T. D. Chung, Y. Choung and J. H. Chung, J. Mater. Chem. B, 2013, 1, 933 DOI: 10.1039/C2TB00274D

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