Issue 5, 2015

Review on Ion Mobility Spectrometry. Part 2: hyphenated methods and effects of experimental parameters

Abstract

Ion Mobility Spectrometry (IMS) is a widely used and ‘well-known’ technique of ion separation in the gaseous phase based on the differences of ion mobilities under an electric field. This technique has received increased interest over the last several decades as evidenced by the pace and advances of new IMS devices available. In this review we explore the hyphenated techniques that are used with IMS, specifically mass spectrometry as an identification approach and a multi-capillary column as a pre-separation approach. Also, we will pay special attention to the key figures of merit of the ion mobility spectrum and how data sets are treated, and the influences of the experimental parameters on both conventional drift time IMS (DTIMS) and miniaturized IMS also known as high Field Asymmetric IMS (FAIMS) in the planar configuration. The present review article is preceded by a companion review article which details the current instrumentation and contains the sections that configure both conventional DTIMS and FAIMS devices. These reviews will give the reader an insightful view of the main characteristics and aspects of the IMS technique.

Graphical abstract: Review on Ion Mobility Spectrometry. Part 2: hyphenated methods and effects of experimental parameters

Article information

Article type
Critical Review
Submitted
19 Jun 2014
Accepted
15 Oct 2014
First published
03 Dec 2014

Analyst, 2015,140, 1391-1410

Review on Ion Mobility Spectrometry. Part 2: hyphenated methods and effects of experimental parameters

R. Cumeras, E. Figueras, C. E. Davis, J. I. Baumbach and I. Gràcia, Analyst, 2015, 140, 1391 DOI: 10.1039/C4AN01101E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements