Issue 18, 2014
From the journal:

Lab on a Chip

Multiplexed immunoassay based on micromotors and microscale tags†

D. Vilela,‡ab   J. Orozco,‡a   G. Cheng,‡ac   S. Sattayasamitsathit,a   M. Galarnyk,a   C. Kan,c   J. Wang*a  and  A. Escarpa*b  

* Corresponding authors

a Department of Nanoengineering, University of California San Diego, La Jolla, California 92093, USA

b Department of Analytical Chemistry, Physical Chemistry and Chemical Engineering, University of Alcalá, E-28871 Alcalá de Henares, Madrid, Spain
E-mail: alberto.escarpa@uah.es

c Department of Chemical Engineering, Tsinghua University, Beijing, China

Abstract

This work reports on the coupling of antibody-functionalized micromotors and microwire-tagged proteins for rapid and multiplexed immunoassays. While micromotor-induced mixing accelerates the immunoreaction, tagging the proteins with microscopic particles of different sizes and shapes allows for their multiplexed discrimination, alerting of the presence of a biological threat.

Graphical abstract: Multiplexed immunoassay based on micromotors and microscale tags

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Article information

DOI
https://doi.org/10.1039/C4LC00596A
Article type
Paper
Submitted
21 May 2014
Accepted
30 Jun 2014
First published
30 Jun 2014

Lab Chip, 2014,14, 3505-3509

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Multiplexed immunoassay based on micromotors and microscale tags

D. Vilela, J. Orozco, G. Cheng, S. Sattayasamitsathit, M. Galarnyk, C. Kan, J. Wang and A. Escarpa, Lab Chip, 2014, 14, 3505 DOI: 10.1039/C4LC00596A

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