Issue 58, 2015
From the journal:

Chemical Communications

Ultrasensitive genotyping with target-specifically generated circular DNA templates and RNA FRET probes†

Haoxian Zhou,a   Hui Wang,a   Chenghui Liu,*a   Honghong Wang,a   Xinrui Duana  and  Zhengping Li*a  

* Corresponding authors

a Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710062, Shaanxi Province, P. R. China
E-mail: liuch@snnu.edu.cn, lzpbd@snnu.edu.cn
Fax: +86 29 81530859
Tel: +86 29 81530859

Abstract

A novel RNA FRET probe that can produce target-dependent signal amplification with the catalysis of RNase H has been developed for detection of rolling circle amplification (RCA) products with greatly improved sensitivity.

Graphical abstract: Ultrasensitive genotyping with target-specifically generated circular DNA templates and RNA FRET probes

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Article information

DOI
https://doi.org/10.1039/C5CC03738G
Article type
Communication
Submitted
05 May 2015
Accepted
10 Jun 2015
First published
22 Jun 2015

Chem. Commun., 2015,51, 11556-11559

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Ultrasensitive genotyping with target-specifically generated circular DNA templates and RNA FRET probes

H. Zhou, H. Wang, C. Liu, H. Wang, X. Duan and Z. Li, Chem. Commun., 2015, 51, 11556 DOI: 10.1039/C5CC03738G

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