Issue 24, 2016

On-chip electromagnetic tweezers – 3-dimensional particle actuation using microwire crossbar arrays

Abstract

Emerging miniaturization technologies for biological and bioengineering applications require precise control over position and actuation of microparticles. While many of these applications call for high-throughput approaches, common tools for particle manipulation, such as magnetic or optical tweezers, suffer from low parallelizability. To address this issue, we introduce a chip-based platform that enables flexible three-dimensional control over individual magnetic microparticles. Our system relies on microwire crossbar arrays for simultaneous generation of magnetic and dielectric forces, which actuate the particles along highly localized traps. We demonstrate the precise spatiotemporal control of individual particles by tracing complex trajectories in three dimensions and investigate the forces that can be generated along different axes. Furthermore, we show that our approach for particle actuation can be parallelized by simultaneously controlling the position and movement of 16 particles in parallel.

Graphical abstract: On-chip electromagnetic tweezers – 3-dimensional particle actuation using microwire crossbar arrays

Supplementary files

Article information

Article type
Paper
Submitted
12 Jul 2016
Accepted
03 Nov 2016
First published
08 Nov 2016
This article is Open Access
Creative Commons BY-NC license

Lab Chip, 2016,16, 4749-4758

On-chip electromagnetic tweezers – 3-dimensional particle actuation using microwire crossbar arrays

P. Rinklin, H. Krause and B. Wolfrum, Lab Chip, 2016, 16, 4749 DOI: 10.1039/C6LC00887A

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