Issue 2, 2019

A single-atom Fe–N4 catalytic site mimicking bifunctional antioxidative enzymes for oxidative stress cytoprotection

Abstract

Atomically dispersed Fe–N4 sites anchored on N-doped porous carbon materials (Fe-SAs/NC) can mimic two antioxidative enzymes of catalase (CAT) and superoxide dismutase (SOD), and therefore serves as a bifunctional single-atom-based enzyme (SAzyme) for scavenging reactive oxygen species (ROS) to remove excess ROS generated during oxidative stress in cells.

Graphical abstract: A single-atom Fe–N4 catalytic site mimicking bifunctional antioxidative enzymes for oxidative stress cytoprotection

Supplementary files

Article information

Article type
Communication
Submitted
10 Oct 2018
Accepted
19 Nov 2018
First published
19 Nov 2018

Chem. Commun., 2019,55, 159-162

A single-atom Fe–N4 catalytic site mimicking bifunctional antioxidative enzymes for oxidative stress cytoprotection

W. Ma, J. Mao, X. Yang, C. Pan, W. Chen, M. Wang, P. Yu, L. Mao and Y. Li, Chem. Commun., 2019, 55, 159 DOI: 10.1039/C8CC08116F

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