Issue 3, 2004

Anti-viral cyclammacrocycles : rapid zinc uptake at physiological pH

Abstract

NMR and UV-vis spectroscopic studies show that Zn(II) binds to cyclam rapidly at micromolar concentrations, an observation relevant to the anti-viral activity and co-receptor binding of anti-HIV cyclams.

Graphical abstract: Anti-viral cyclam macrocycles : rapid zinc uptake at physiological pH

Supplementary files

Article information

Article type
Communication
Submitted
14 Oct 2003
Accepted
04 Dec 2003
First published
06 Jan 2004

Chem. Commun., 2004, 306-307

Anti-viral cyclam macrocycles : rapid zinc uptake at physiological pH

S. J. Paisey and P. J. Sadler, Chem. Commun., 2004, 306 DOI: 10.1039/B312752B

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