Issue 14, 2011
From the journal:

Chemical Communications

Investigation of the stability of labelled nanoparticles for SE(R)RS measurements in cells†

Narayana M. S. Sirimuthu,a   Christopher D. Symea  and  Jonathan M. Cooper*a  

* Corresponding authors

a Bioelectronics Research Group, School of Engineering, University of Glasgow, Glasgow, UK
E-mail: jon.cooper@glasgow.ac.uk
Tel: +44 (0)1413305218

Abstract

We explore the long-term stability of two different classes of labelled nanoparticles as intracellular SE(R)RS probes. Whilst chemisorbed labels gave stable responses inside cells for extended periods of time, signals from physisorbed labels could only be measured for short periods of time. These results help inform strategies for cellular imaging using vibrational spectroscopies.

Graphical abstract: Investigation of the stability of labelled nanoparticles for SE(R)RS measurements in cells

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Article information

DOI
https://doi.org/10.1039/C0CC05723A
Article type
Communication
Submitted
22 Dec 2010
Accepted
14 Feb 2011
First published
28 Feb 2011

Chem. Commun., 2011,47, 4099-4101

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Investigation of the stability of labelled nanoparticles for SE(R)RS measurements in cells

N. M. S. Sirimuthu, C. D. Syme and J. M. Cooper, Chem. Commun., 2011, 47, 4099 DOI: 10.1039/C0CC05723A

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