Issue 39, 2011
From the journal:

Journal of Materials Chemistry

One-pot self-assembly of mesoporous silicananoparticle-based pH-responsive anti-cancer nano drug delivery system†

Qianjun He,a   Yu Gao,b   Lingxia Zhang,a   Wenbo Bu,a   Hangrong Chen,a   Yaping Lib  and  Jianlin Shi*a  

* Corresponding authors

a State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Ding-Xi Rd, Shanghai, P. R. China
E-mail: jlshi@sunm.shcnc.ac.cn
Fax: +86 21 52413122
Tel: +86 21 52412714

b Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong-Zhi Road, Shanghai, P. R. China

Abstract

A mesoporous silica nanoparticle (MSN)-based pH-responsive nano drug delivery system (hydrophobic drugs@micelles@MSNs) is constructed by a one-pot self-assembly strategy, exhibiting improved drug efficacy against both drug-resistant and drug-sensitive cancer cells.

Graphical abstract: One-pot self-assembly of mesoporous silica nanoparticle-based pH-responsive anti-cancer nano drug delivery system

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Article information

DOI
https://doi.org/10.1039/C1JM13598H
Article type
Communication
Submitted
28 Jul 2011
Accepted
16 Aug 2011
First published
01 Sep 2011

J. Mater. Chem., 2011,21, 15190-15192

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One-pot self-assembly of mesoporous silica nanoparticle-based pH-responsive anti-cancer nano drug delivery system

Q. He, Y. Gao, L. Zhang, W. Bu, H. Chen, Y. Li and J. Shi, J. Mater. Chem., 2011, 21, 15190 DOI: 10.1039/C1JM13598H

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