Amidines bearing benzofuroxan or benzimidazole 1,3-dioxide core scaffolds as Trypanosoma cruzi-inhibitors: structural basis for their interactions with cruzipain†
Abstract
* Corresponding authors
a
Grupo de Química Medicinal-Laboratorio de Química Orgánica, Facultad de Ciencias-Facultad de Química, Universidad de la República, Iguá 4225, Montevideo, Uruguay
E-mail:
megonzal@fq.edu.uy, hcerecet@fq.edu.uy
Fax: +598 2 5250749
Tel: +598 2 5258618 (ext. 216)
b Instituto de Química Médica, CSIC, Madrid, Spain
c Multiusers Analysis by NMR Laboratory – LAMAR and Laboratory of Analysis and Development of Enzyme Inhibitors - LADIE, NPPN, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
A. Merlino, D. Benitez, N. E. Campillo, J. A. Páez, L. W. Tinoco, M. González and H. Cerecetto, Med. Chem. Commun., 2012, 3, 90 DOI: 10.1039/C1MD00223F
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