Issue 1, 2012

Advances in metal–carbene complexes as potent anti-cancer agents

Abstract

This critical review is an updated survey of metal–carbenes as potential anticancer chemotherapeutics. We report on the recent advances in the discovery of N-heterocyclic carbenes, acyclic diamino carbenes and abnormal NHCs associated with metals from groups 10 and 11 that displayed antiproliferative activity and emphasize, when possible, their molecular target(s) and their mechanism of action.

Graphical abstract: Advances in metal–carbene complexes as potent anti-cancer agents

Article information

Article type
Critical Review
Submitted
02 Aug 2011
Accepted
06 Oct 2011
First published
25 Oct 2011

Metallomics, 2012,4, 23-32

Spotlight

Advertisements