Issue 22, 2011

Cubosomes for ruthenium complex delivery: formulation and characterization

Abstract

An amphiphilic ruthenium-based molecule (DOPURu) with potential antineoplastic activity has been synthesized, and its aggregation behavior in the presence of phospholipids has been investigated. A very rich variety of aggregates has been found, spanning from vesicles to cubic bicontinuous phases. Cubosomes here presented represent one of the first systems with potential use for medical therapy.

Graphical abstract: Cubosomes for ruthenium complex delivery: formulation and characterization

Supplementary files

Article information

Article type
Communication
Submitted
13 Jul 2011
Accepted
12 Sep 2011
First published
03 Oct 2011

Soft Matter, 2011,7, 10577-10580

Cubosomes for ruthenium complex delivery: formulation and characterization

G. Mangiapia, M. Vaccaro, G. D'Errico, H. Frielinghaus, A. Radulescu, V. Pipich, A. M. Carnerup and L. Paduano, Soft Matter, 2011, 7, 10577 DOI: 10.1039/C1SM06323E

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