Issue 55, 2012
From the journal:

Chemical Communications

Personal glucose sensor for point-of-care early cancer diagnosis†

Jiao Su,a   Jin Xu,a   Ying Chen,a   Yun Xiang,*a   Ruo Yuana  and  Yaqin Chaia  

* Corresponding authors

a Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China
E-mail: yunatswu@swu.edu.cn
Fax: +86-23-68252277
Tel: +86-23-68253172

Abstract

Early POC diagnosis of cancer is demonstrated by using multi-invertase conjugated microsphere labels and a personal glucose sensor (PGS) transducer. The invertase, which catalyzes the hydrolysis of sucrose to glucose, enables the PGS to detect target analytes beyond glucose, and the numerous invertase labels involved in each antibody–antigen binding event lead to significantly amplified PGS readings for sensitive protein detection.

Graphical abstract: Personal glucose sensor for point-of-care early cancer diagnosis

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Article information

DOI
https://doi.org/10.1039/C2CC32729E
Article type
Communication
Submitted
17 Apr 2012
Accepted
18 May 2012
First published
18 May 2012

Chem. Commun., 2012,48, 6909-6911

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Personal glucose sensor for point-of-care early cancer diagnosis

J. Su, J. Xu, Y. Chen, Y. Xiang, R. Yuan and Y. Chai, Chem. Commun., 2012, 48, 6909 DOI: 10.1039/C2CC32729E

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