Issue 5, 2012
From the journal:

Green Chemistry

The synthesis of N-heterocycles via copper/TEMPO catalysed aerobic oxidation of amino alcohols†

James C. A. Flanagan,a   Laura M. Dornan,a   Mark G. McLaughlin,a   Niall G. McCreanor,a   Matthew J. Cook*a  and  Mark J. Muldoon*a  

* Corresponding authors

a School of Chemistry and Chemical Engineering, Queen's University Belfast, David Keir Building, Stranmillis Road, Belfast, Northern Ireland
E-mail: m.cook@qub.ac.uk, m.j.muldoon@qub.ac.uk
Tel: +44 (0) 28 9097 4682

Abstract

N-Heterocycles can be prepared using alcohol oxidation as a key synthetic step. Herein we report studies exploring the potential of Cu/TEMPO as an aerobic oxidation catalyst for the synthesis of substituted indoles and quinolines.

Graphical abstract: The synthesis of N-heterocycles via copper/TEMPO catalysed aerobic oxidation of amino alcohols

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Article information

DOI
https://doi.org/10.1039/C2GC35062A
Article type
Communication
Submitted
13 Jan 2012
Accepted
24 Feb 2012
First published
28 Feb 2012
This article is Open Access

Green Chem., 2012,14, 1281-1283

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The synthesis of N-heterocycles via copper/TEMPO catalysed aerobic oxidation of amino alcohols

J. C. A. Flanagan, L. M. Dornan, M. G. McLaughlin, N. G. McCreanor, M. J. Cook and M. J. Muldoon, Green Chem., 2012, 14, 1281 DOI: 10.1039/C2GC35062A

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