Issue 11, 2012

Direct synthesis of dextran-coated superparamagnetic iron oxide nanoparticles in a capillary-based droplet reactor

Abstract

We describe the controlled synthesis of dextran-coated superparamagnetic iron oxide nanoparticles (SPIONs) using a stable passively-driven capillary-based droplet reactor. High quality highly crystalline particles were obtained with a narrow size distribution of mean diameter 3.6 nm and standard deviation 0.8 nm. The particles were evaluated for use in MRI, and found to exhibit a large saturation magnetisation of 58 emu/g and a high T2 relaxivity of 66 mM−1s−1 at 4.7 T, signifying good MRI contrast enhancement properties.

Graphical abstract: Direct synthesis of dextran-coated superparamagnetic iron oxide nanoparticles in a capillary-based droplet reactor

Supplementary files

Article information

Article type
Paper
Submitted
13 Jan 2012
Accepted
20 Jan 2012
First published
26 Jan 2012

J. Mater. Chem., 2012,22, 4704-4708

Direct synthesis of dextran-coated superparamagnetic iron oxide nanoparticles in a capillary-based droplet reactor

K. Kumar, A. M. Nightingale, S. H. Krishnadasan, N. Kamaly, M. Wylenzinska-Arridge, K. Zeissler, W. R. Branford, E. Ware, A. J. deMello and J. C. deMello, J. Mater. Chem., 2012, 22, 4704 DOI: 10.1039/C2JM30257H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements