Issue 21, 2013

Facile in vitro hydroxyapatite remineralization of human enamel with remarkable hardness

Abstract

The fabrication of enamel-mimicking material for clinical enamel remineralization remains a challenge. In this work, we proposed a facile and economical biomimetic strategy for achieving in vitro hydroxyapatite (HAP) remineralization on eroded human enamel using nacre water-soluble matrix (WSM) as template. X-ray diffraction (XRD) analysis and Fourier transformed infrared (FTIR) spectroscopy demonstrated that WSM facilitated the formation of HAP with a similar composition and structure to the natural enamel under mild conditions. Microscopic investigations revealed that the WSM-induced HAP nanorods were well bundled in parallel and densely arranged into highly-ordered units as compared to loose and disordered HAP crystals formed in the absence of WSM. The ideal features, smoothness and hardness of the WSM-induced HAP were further confirmed by the atomic force microscope (AFM) and digital Vicker's Hardness tester. We also discussed the role of WSM in inducing the highly-ordered HAP. The finding in this work provides new threads for the development of novel dental materials for clinical caries management.

Graphical abstract: Facile in vitro hydroxyapatite remineralization of human enamel with remarkable hardness

Supplementary files

Article information

Article type
Paper
Submitted
30 Nov 2012
Accepted
21 Mar 2013
First published
21 Mar 2013

CrystEngComm, 2013,15, 4351-4356

Facile in vitro hydroxyapatite remineralization of human enamel with remarkable hardness

X. Li, D. Pan, S. Lin, Z. Zhuang and Z. Lin, CrystEngComm, 2013, 15, 4351 DOI: 10.1039/C3CE26947G

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