Issue 7, 2013

Cost-effective and rapid blood analysis on a cell-phone

Abstract

We demonstrate a compact and cost-effective imaging cytometry platform installed on a cell-phone for the measurement of the density of red and white blood cells as well as hemoglobin concentration in human blood samples. Fluorescent and bright-field images of blood samples are captured using separate optical attachments to the cell-phone and are rapidly processed through a custom-developed smart application running on the phone for counting of blood cells and determining hemoglobin density. We evaluated the performance of this cell-phone based blood analysis platform using anonymous human blood samples and achieved comparable results to a standard bench-top hematology analyser. Test results can either be stored on the cell-phone memory or be transmitted to a central server, providing remote diagnosis opportunities even in field settings.

Graphical abstract: Cost-effective and rapid blood analysis on a cell-phone

Article information

Article type
Paper
Submitted
22 Dec 2012
Accepted
22 Jan 2013
First published
22 Jan 2013

Lab Chip, 2013,13, 1282-1288

Cost-effective and rapid blood analysis on a cell-phone

H. Zhu, I. Sencan, J. Wong, S. Dimitrov, D. Tseng, K. Nagashima and A. Ozcan, Lab Chip, 2013, 13, 1282 DOI: 10.1039/C3LC41408F

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