Issue 12, 2013

Electrochemically-gated delivery of analyte bands in microfluidic devices using bipolar electrodes

Abstract

A method for controlling enrichment, separation, and delivery of analytes into different secondary microchannels using simple microfluidic architecture is described. The approach, which is based on bipolar electrochemistry, requires only easily fabricated electrodes and a low-voltage DC power supply: no pumps or valves are necessary. Upon application of a voltage between two driving electrodes, passive bipolar electrodes (BPEs) are activated that result in formation of a local electric field gradient. This gradient leads to separation and enrichment of a pair of fluorescent analytes within a primary microfluidic channel. Subsequently, other passive BPEs can be activated to deliver the enriched tracers to separate secondary microchannels. The principles and performance underpinning the method are described.

Graphical abstract: Electrochemically-gated delivery of analyte bands in microfluidic devices using bipolar electrodes

Supplementary files

Article information

Article type
Paper
Submitted
09 Mar 2013
Accepted
17 Apr 2013
First published
08 May 2013

Lab Chip, 2013,13, 2292-2299

Electrochemically-gated delivery of analyte bands in microfluidic devices using bipolar electrodes

K. Scida, E. Sheridan and R. M. Crooks, Lab Chip, 2013, 13, 2292 DOI: 10.1039/C3LC50321F

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