Issue 14, 2019
From the journal:

Chemical Communications

Mineral surfaces select for longer RNA molecules†

Ryo Mizuuchi, ORCID logo *a   Alex Blokhuis, ORCID logo bc   Lena Vincent,d   Philippe Nghe,b   Niles Lehman ORCID logo a  and  David Baumd  

* Corresponding authors

a Department of Chemistry, Portland State University, Portland, OR 97201, USA
E-mail: mizuuchi@pdx.edu

b Laboratory of Biochemistry, PSL Research University, ESPCI, 10 rue Vauquelin, F-75231 Paris Cedex 05, France

c Gulliver Laboratory, UMR CNRS 7083, PSL Research University, ESPCI, 10 rue Vauquelin, F-75231 Paris Cedex 05, France

d Department of Botany, Wisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, WI-53715, USA

Abstract

We report empirically and theoretically that multiple prebiotic minerals can selectively accumulate longer RNAs, with selectivity enhanced at higher temperatures. We further demonstrate that surfaces can be combined with a catalytic RNA to form longer RNA polymers, supporting the potential of minerals to develop genetic information on the early Earth.

Graphical abstract: Mineral surfaces select for longer RNA molecules

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Article information

DOI
https://doi.org/10.1039/C8CC10319D
Article type
Communication
Submitted
31 Dec 2018
Accepted
17 Jan 2019
First published
17 Jan 2019

Chem. Commun., 2019,55, 2090-2093

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Mineral surfaces select for longer RNA molecules

R. Mizuuchi, A. Blokhuis, L. Vincent, P. Nghe, N. Lehman and D. Baum, Chem. Commun., 2019, 55, 2090 DOI: 10.1039/C8CC10319D

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