Issue 18, 2021

Lipids as versatile solvents for chemical synthesis

Abstract

Development of safe, renewable, cheap and versatile solvents is a longstanding challenge in chemistry. We show here that vegetable oils and related systems can become prominent solvents for organic synthesis. Suzuki–Miyaura, Hiyama, Stille, Sonogashira and Heck cross-couplings proceed with quantitative yields in a range of vegetable oils, fish oil, butter and waxes used as solvents. Appropriate methodologies for high-throughput screening and sustainable isolation techniques applicable for vegetable oils and related lipids are presented.

Graphical abstract: Lipids as versatile solvents for chemical synthesis

Supplementary files

Article information

Article type
Paper
Submitted
30 Jun 2021
Accepted
17 Aug 2021
First published
23 Aug 2021

Green Chem., 2021,23, 7219-7227

Lipids as versatile solvents for chemical synthesis

A. Gevorgyan, K. H. Hopmann and A. Bayer, Green Chem., 2021, 23, 7219 DOI: 10.1039/D1GC02311J

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