Platinum-catalysed 1,4-diboration of 1,3-dienes
Abstract
The chiral diborane(4) compounds B2[R,R-O2CH(CO2Me)CH(CO2Me)]2, B2(S-O2CH2CHPh)2, B2(R,R-O2CHPhCHPh)2 and B2(O2C20H12)2 (O2C20H12 = 1,7′-bi-2-naphtholate) have been synthesized. All four compounds have been characterised by X-ray crystallography, the latter as a racemate. The B–B bond oxidative-addition reactions of the first three compounds with [Pt(PPh3)2(η-C2H4)] resulted in the platinum(II) bis(boryl) complexes cis-[Pt(PPh3)2{B[R,R-O2CH(CO2Me)CH(CO2Me)]}2], cis-[Pt(PPh3)2{B(S-O2CH2CHPh)}2] and cis-[Pt(PPh3)2{B(R,R-O2CHPhCHPh)}2]; the former two were also characterised by X-ray crystallography. The platinum-catalysed diborations of a range of prochiral 1,3-dienes with the compounds B2[R,R-O2CH(CO2Me)CH(CO2Me)]2, B2(S-O2CH2CHPh)2 and B2(R,R-O2CHPhCHPh)2 were studied. Although these reactions were clean and quantitative, observed product d.e.s (measured by 1H NMR spectroscopy) were low or non-existent indicating that chirality transfer from the diborane(4) diolate groups to the diene diboration product is not efficient in these cases.