Issue 21, 1999

An enantioselective synthesis of heteroaromatic N-tosyl α-amino acids

Abstract

A new synthesis of optically active β-indolyl and pyrrolyl N-tosyl α-amino acids has been developed which uses readily available starting materials and proceeds with a high degree of enantioselection, giving the α-amino acids with up to 96% enantiomeric purity in 89% yield using 1–5 mol% of a chiral copper(I)–Tol-BINAP catalyst.

Article information

Article type
Paper

Chem. Commun., 1999, 2233-2234

An enantioselective synthesis of heteroaromatic N-tosyl α-amino acids

M. Johannsen, Chem. Commun., 1999, 2233 DOI: 10.1039/A906758B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements