Issue 17, 2001
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Isolation, structure and synthesis of mahafacyclin B, a cyclic heptapeptide from the latex of Jatropha mahafalensis

Carine Baraguey,a   Alain Blond,a   Florine Cavelier,b   Jean-Louis Pousset,a   Bernard Bodoa  and  Catherine Auvin-Guette*a  

* Corresponding authors

a Laboratoire de Chimie des Substances Naturelles, ESA 8041 CNRS, IFR 63 CNRS, Muséum National d'Histoire Naturelle, 63 rue Buffon, France

b UMR 5810, Laboratoire des Aminoacides, Peptides et Protéines, Université Montpellier II, Place Eugène Bataillon, France

Abstract

Mahafacyclin B is a cyclic heptapeptide with antimalarial activity isolated from the latex of Jatropha mahafalensis. The structure is elucidated by chemical degradation, tandem mass spectrometry, homo- and heteronuclear NMR experiments, and confirmed by synthesis.

Graphical abstract: Isolation, structure and synthesis of mahafacyclin B, a cyclic heptapeptide from the latex of Jatropha mahafalensis

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Article information

DOI
https://doi.org/10.1039/B008538N
Article type
Paper
Submitted
23 Oct 2000
Accepted
22 Jun 2001
First published
16 Aug 2001

J. Chem. Soc., Perkin Trans. 1, 2001, 2098-2103

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Isolation, structure and synthesis of mahafacyclin B, a cyclic heptapeptide from the latex of Jatropha mahafalensis

C. Baraguey, A. Blond, F. Cavelier, J. Pousset, B. Bodo and C. Auvin-Guette, J. Chem. Soc., Perkin Trans. 1, 2001, 2098 DOI: 10.1039/B008538N

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