Issue 5, 2002

A novel and direct synthesis of indolesvia catalytic reductive annulation of nitroaromatics with alkynes

Abstract

Indoles are produced regioselectively and in moderate yields from the reactions of nitroaromatics with alkynes catalyzed by [CpM(CO)2]2 (1; [(η5-C5H5)Fe(CO)2]2; [(η5-C5Me5)Fe(CO)2]2; [(η5-C5Me5)Ru(CO)2]2) under carbon monoxide.

Graphical abstract: A novel and direct synthesis of indoles via catalytic reductive annulation of nitroaromatics with alkynes

Supplementary files

Article information

Article type
Communication
Submitted
13 Nov 2001
Accepted
14 Jan 2002
First published
07 Feb 2002

Chem. Commun., 2002, 484-485

A novel and direct synthesis of indoles via catalytic reductive annulation of nitroaromatics with alkynes

A. Penoni and K. M. Nicholas, Chem. Commun., 2002, 484 DOI: 10.1039/B110370A

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