Issue 7, 2002

Photoremovable protecting groups: reaction mechanisms and applications

Abstract

Photolabile protecting groups enable biochemists to control the release of bioactive compounds in living tissue. ‘Caged compounds’ (photoactivatable bioagents) have become an important tool to study the events that follow chemical signalling in, e.g., cell biology and the neurosciences. The possibilities are by no means exhausted. Progress will depend on the development of photoremovable protecting groups that satisfy the diverse requirements of new applications—a challenging task for photochemists.

Graphical abstract: Photoremovable protecting groups: reaction mechanisms and applications

Article information

Article type
Perspective
Submitted
21 Jan 2002
Accepted
01 May 2002
First published
06 Jun 2002

Photochem. Photobiol. Sci., 2002,1, 441-458

Photoremovable protecting groups: reaction mechanisms and applications

A. P. Pelliccioli and J. Wirz, Photochem. Photobiol. Sci., 2002, 1, 441 DOI: 10.1039/B200777K

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