Issue 18, 2002
From the journal:

Chemical Communications

A new approach to oligonucleotidelabelling using Diels–Alder cycloadditions and detection by SERRS†

Ljiljana Fruk,a   Antonio Grondin,a   W. Ewen Smitha  and  Duncan Graham*a  

* Corresponding authors

a Department of Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow, UK
E-mail: duncan.graham@strath.ac.uk
Fax: 0141 552 0876
Tel: 0141 548 4701

Abstract

Diels–Alder cycloaddition has been used to add a benzotriazole azo dye to a diene tagged oligonucleotide to generate unique SERRS signals at 10 attomoles.

Graphical abstract: A new approach to oligonucleotide labelling using Diels–Alder cycloadditions and detection by SERRS

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Article information

DOI
https://doi.org/10.1039/B204790J
Article type
Communication
Submitted
17 May 2002
Accepted
29 Jul 2002
First published
08 Aug 2002

Chem. Commun., 2002, 2100-2101

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A new approach to oligonucleotide labelling using Diels–Alder cycloadditions and detection by SERRS

L. Fruk, A. Grondin, W. E. Smith and D. Graham, Chem. Commun., 2002, 2100 DOI: 10.1039/B204790J

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