Issue 21, 2002

Proline-catalysed asymmetric aldol reaction in the room temperature ionic liquid [bmim]PF6

Abstract

Proline-catalysed asymmetric direct aldol reaction of different aromatic aldehydes with acetone and several other ketones in the room temperature ionic liquid 1-n-butyl-3-methylimidazolium hexafluorophosphate achieved good yields of aldolisation products with reasonable enantioselectivities, even when just 1–5% of proline was used as the catalyst; immobilisation of the catalyst in an ionic liquid phase offers simple product isolation and reuse of the catalytical system in subsequent reactions.

Graphical abstract: Proline-catalysed asymmetric aldol reaction in the room temperature ionic liquid [bmim]PF6

Supplementary files

Article information

Article type
Communication
Submitted
16 Jul 2002
Accepted
09 Sep 2002
First published
26 Sep 2002

Chem. Commun., 2002, 2510-2511

Proline-catalysed asymmetric aldol reaction in the room temperature ionic liquid [bmim]PF6

P. Kotrusz, I. Kmentová, B. Gotov, Š. Toma and E. Solčániová, Chem. Commun., 2002, 2510 DOI: 10.1039/B206911C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements