Issue 1, 2003

Definitive identification of cysteine and glutathione complexes of bismuth by mass spectrometry: assessing the biochemical fate of bismuth pharmaceutical agents

Abstract

Solutions containing BiCl3, bismuth subsalicylate or Bi(NO3)3 with L-cysteine, DL-homocysteine, D-methionine or glutathione have been examined by electrospray mass spectrometry. Prominent peaks are assigned to bismuth complexes of these biomolecules and provide insight towards understanding the bioactivity of bismuth compounds.

Graphical abstract: Definitive identification of cysteine and glutathione complexes of bismuth by mass spectrometry: assessing the biochemical fate of bismuth pharmaceutical agents

Article information

Article type
Communication
Submitted
25 Oct 2002
Accepted
18 Nov 2002
First published
03 Dec 2002

Chem. Commun., 2003, 146-147

Definitive identification of cysteine and glutathione complexes of bismuth by mass spectrometry: assessing the biochemical fate of bismuth pharmaceutical agents

N. Burford, M. D. Eelman, D. E. Mahony and M. Morash, Chem. Commun., 2003, 146 DOI: 10.1039/B210570E

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