Issue 13, 2003
From the journal:

Chemical Communications

Synthesis of a hyaluronan neoglycopolymer by ring-opening metathesis polymerization†

Suri Iyer,a   Shyam Rele,a   Gabriela Grasa,b   Steven Nolanb  and  Elliot L. Chaikof*ac  

* Corresponding authors

a Department of Surgery and Biomedical Engineering, Emory University, Atlanta, GA 30322, USA
E-mail: echaiko@emory.edu
Fax: 1-404-727-3660
Tel: 1-404-727-8413

b University of New Orleans, Department of Chemistry, New Orleans, LA 70148, USA

c School of Chemical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA

Abstract

A hyaluronan (HA)-derived disaccharide was synthesized bearing an n-pentenyl spacer arm, which facilitated disaccharide derivatization with a norbornene template. Subsequent ring opening metathesis polymerization of the monomer produced an HA-mimetic neoglycopolymer of low polydispersity.

Graphical abstract: Synthesis of a hyaluronan neoglycopolymer by ring-opening metathesis polymerization

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Article information

DOI
https://doi.org/10.1039/B301734F
Article type
Communication
Submitted
12 Feb 2003
Accepted
29 Apr 2003
First published
30 May 2003

Chem. Commun., 2003, 1518-1519

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Synthesis of a hyaluronan neoglycopolymer by ring-opening metathesis polymerization

S. Iyer, S. Rele, G. Grasa, S. Nolan and E. L. Chaikof, Chem. Commun., 2003, 1518 DOI: 10.1039/B301734F

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