Issue 12, 2003
From the journal:

Chemical Communications

Investigation of the early stages in soraphen A biosynthesis

Alison M. Hill,†*a   Betty L. Thompson,a   Jonathan P. Harrisa  and  Roger Segreta  

* Corresponding authors

a Department of Chemistry, King's College London, Strand, London, UK
E-mail: a.m.hill@ex.ac.uk
Fax: +44 (0)1392 263434
Tel: +44 (0)1392 263467

Abstract

The unusual benzoate starter unit in soraphen A derives from phenylalanine via cinnamate in a β-oxidative (plant-like) pathway; 3-phenyl-3-hydroxypropanoate incorporates directly into soraphen by loading onto module 2 of the PKS and indirectly from the β-oxidative pathway to generate benzoyl CoA.

Graphical abstract: Investigation of the early stages in soraphen A biosynthesis

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Article information

DOI
https://doi.org/10.1039/B303542P
Article type
Communication
Submitted
28 Mar 2003
Accepted
15 Apr 2003
First published
19 May 2003

Chem. Commun., 2003, 1358-1359

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Investigation of the early stages in soraphen A biosynthesis

A. M. Hill, B. L. Thompson, J. P. Harris and R. Segret, Chem. Commun., 2003, 1358 DOI: 10.1039/B303542P

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