Issue 5, 2004

The Sonogashira coupling reaction catalyzed by ultrafine nickel(0) powder

Abstract

The Sonogashira coupling reaction catalyzed by ultrafine nickel(0) powder has been developed; terminal alkynes couple with aryl, alkenyl iodide and aryl bromide in the presence of cuprous iodide, triphenylphosphine, potassium hydroxide and ultrafine particle nickel(0) to provide the corresponding cross-coupling products with high yields.

Graphical abstract: The Sonogashira coupling reaction catalyzed by ultrafine nickel(0) powder

Article information

Article type
Communication
Submitted
15 Nov 2003
Accepted
15 Dec 2003
First published
27 Jan 2004

Chem. Commun., 2004, 514-515

The Sonogashira coupling reaction catalyzed by ultrafine nickel(0) powder

L. Wang, P. Li and Y. Zhang, Chem. Commun., 2004, 514 DOI: 10.1039/B314246A

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